Africa is the most underdeveloped continent in the world. Since infrastructure is very limited, transportation of anything, including e.g. life-saving medicines, becomes a challenge. United Nations explores whether it is possible to deliver HIV test samples by drones in Malawi. In Rwanda there are also some tests conducted checking if delivery of blood and life-saving cargo to remote hospitals is possible. These are only few examples of drone providing humanitarian help but the opportunities are enormous. Transportation of anything in Africa takes weeks. With drones, it can be shortened to hours. Although drones are not a quick-fix solution for rural Africa, and many issues such as e.g. costs or reaction of people for flying objects have to be resolved, but the technology is already developed and can soon be used to bring progress in the most remote and hard to reach places.